Uterine cancer is on the rise in the United States, and Black women are expected to bear the brunt of the increase. A new study projects that by 2050, incidence-based mortality from uterine cancer will nearly triple among Black women, reaching 27.9 deaths per 100,000—compared to 11.2 per 100,000 in White women.
Currently, Black women already face a mortality rate twice as high as other racial and ethnic groups. The study, led by researchers at Columbia University, used a microsimulation model to forecast trends through 2050. It found that while both Black and White women will see increases in uterine cancer cases, the rise in aggressive nonendometrioid tumors will be far more pronounced in Black women.
Lead author Dr. Jason D. Wright pointed to multiple contributing factors: Black women are more likely to be diagnosed with aggressive cancer types, face delays in diagnosis, and experience treatment delays. These disparities compound to create worse outcomes.
The research team also tested hypothetical screening strategies. They found that introducing screening at age 55 could significantly reduce cancer incidence—lasting up to 16 years in Black women. However, no routine screening currently exists for uterine cancer.
The findings underscore the urgent need for targeted prevention and early detection strategies. Without intervention, the racial gap in uterine cancer outcomes is poised to widen even further.
See “Uterine Cancer Incidence and Mortality Rates Projected to Rise Substantially by 2050” (July 2, 2025)
